93EVALUATION OF ANTIOXIDANT POTENTIAL OF KARISALAI KARPA CHOORNAM- A POLY HERBAL SIDDHA FORMULATIONFree radical scavenging activity of ethanolic extract of Karisalai Karpa Choornam (KKC) was carried out for proving its utility in reactive oxygen species (ROS) mediated diseases. The invitro antioxidant potential of Karisalai Karpa Choornam was screened by DPPH scavenging assay, Superoxide anion scavenging activity assay, reducing power activity assay, metal chelation, and total antioxidant assay. The results of the present study showed that the ethanolic extract of KKC exhibited marked antioxidant activity. The antioxidant potential of KKC may be due to the presence of active phytochemical constituents such as phenolics and flavonoids. The antioxidant potential was found to be concentration dependent and may be attributed to the presence of bioactive compounds in the KKC. The results of the present study concluded that the extract is a source of natural antioxidants which might be helpful in preventing the oxidative stress mediated diseases and aging.karthikpharmawing@gmail.comResearch522015Karisalai Karpa Choornam,Reactive oxygen species,Antioxidant,DPPH, Superoxide anion,Metal chelationKarthikeyan Muthusamy,V.Gopal 2Faculty of Pharmacy, PRIST University, Thanjavur-614904, Tamilnadu, India,College of Pharmacy, Mother Theresa Post Graduate and Research Institute of Health Sciences (A Govt. of Puducherry institution), Pudhucherry-605006, India