77ANTIFUNGAL ACTIVITY OF ENICOSTEMA AXILLARE LAMMedicinal plants play a key role in human health care. It has been estimated that 80% world’s population depend upon herbal based medicines. Superficial fungal infections of skin affect millions of people throughout the world. Enicostema axillare is a common Indian medicinal plant belonging to the family Gentinaceae was selected and screened for the phyto chemical compounds and anti-fungal activity. Samples collected from the skin infected patients. The anti-fungal activity was studied only on the predominant fungal pathogens Trichopyton rubrum and Trichophyton mentagraphytes. The drug at the concentration of 6000g /ml showed a marked inhibitory zonedrbharathajothi@gmail.comResearch512015Phytochemical,Antifungal,Enicostema axillar,TrichopytonP. Bharathajothi,C.T.Bhaaskaran,S. TamilselviAssistant Professor, Dept. of Siddha Medicine, Tamil University, Thanjavur, Tamilnadu, India,Assistant Professor, P.G. Dept. of Plant Science, Avvaiyar Govt.College for Womens, Karaikal, U.T.of Puducherry, India,Assistant Professor, Dept. of Pharmacology, Sairam Siddha Medical College, Thambaram, Chennai, Tamilnadu, India