22VARIATION IN IMMUNOLOGICAL PARAMETER IN ALZHEIMER DISEASEAlzheimer disease is complex neurological disorder, which can be arise any ages most probably found in old person. Several authors have been studied immunological parameter like IgG, IgM, and IgA in AD. Underlying the importance of imbalance in the explanation of the etiopathogenesis and progress of same form of AD. An early diagnosis of A.D. is important because changes in central nerves system respond well to immu nomodulatory treatment in the early course of disease. The value of immunoglobulin IgG, IgM and IgA were measured in serum of patients along with AD and compared with healthy control person .We found the mean value of IgA is higher than healthy normal control and the level of IgM is found to less than in healthy control person, where as no difference is found in IgG level of patient suffering from AD with normal .v_05kumar@rediffmail.comResearch312013Alzheimer disease (AD),immunological parameter IgG,IgM and IgA and statistical analysisVinod Kumar,Vinit Raj,S.K SharmaMember of Medical Research Unit Department Of Physics, D. A. V. (P.G) College, Muzaffarnagar, U.P, India, Pin Code -251001, India,Department of Pharmaceutical Chemistry (Pharmacy), S. D. College of Pharmacy and Vocational Studies, Muzaffarnagar, U.P. India, Pin code-251001, India,Department of Environmental Studies, University of Delhi -110007, India